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Project Areas
The Collaborative Reserach Group SFB 852 consists of 4 project areas.
In Project Area A, the intestinal microbiota and the intestinal viral flora of the pig, of which only little is known, will be examined using modern molecular methods. The effects of a transgenic, and as a result of its cystatin expression, immunmodulatory Escherichia coli strain (Nissle) and the molecular mechanisms of the immunmodulatory effects of Enterococcus faecium will be characterized using molecular and proteomic methods.
In Project Area B, effects on the physiology of epithelial transport, the intestinal barrier function, gene expression as well as regulatory processes, including the significance of the microRNAs, congenital immune functions and the potential effects of zinc on the structure of DNA will be investigated. Furthermore, infection studies using Salmonella typhimurium, Campylobacter coli and viruses will be conducted under varing feeding conditions in piglets.
Project Area C is comprised of several service projects. A service and bioinformatics platform will be available for members of the SFB (C2). The animals used for the experiments will be kept at the Institut für Tierernährung within the framework of Project C3.
The Integrated Post-Graduate Program (D) is a central element of the SFB 852, and will provide a interdisciplinary, international work environment for the junior scientists.
